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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIAA0664 All Species: 19.09
Human Site: S1123 Identified Species: 35
UniProt: O75153 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75153 NP_056044.3 1309 146670 S1123 G V M E Y D L S L R F L E N A
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_548323 1501 166268 S1315 G V M E Y D L S L R F L E N A
Cat Felis silvestris
Mouse Mus musculus Q5SW19 1315 148050 S1125 G V M E Y D L S L R F L E N A
Rat Rattus norvegicus XP_001080615 1352 151608 S1166 G V M E Y D L S L R F L E N A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509391 982 108607 T805 L P N G D V A T G L A L G K E
Chicken Gallus gallus XP_415920 1293 145294 A1116 A N S Q L S T A L N L L Y R A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A0JMD0 1400 155792 G1221 A L L D S N I G L V L H G V M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster A1ZAB5 1448 160833 S1248 A L G E Y E L S L R F I E H A
Honey Bee Apis mellifera XP_624898 1290 145677 H1113 L L V C G E D H P E V A L L D
Nematode Worm Caenorhab. elegans P34466 1247 139903 G1066 Y L M N L V F G E K H P V M A
Sea Urchin Strong. purpuratus XP_001198284 1101 124381 S924 R T N T S W S S L T P S D L W
Poplar Tree Populus trichocarpa XP_002314020 1343 146561 A1076 A L R Y L Q E A L K K N E R L
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7RY84 1211 135142 A1011 Q R G D S K E A L L Y A R H A
Conservation
Percent
Protein Identity: 100 N.A. N.A. 83.3 N.A. 94.9 89.9 N.A. 60.8 83.1 N.A. 75 N.A. 52 59.8 39.9 51.9
Protein Similarity: 100 N.A. N.A. 85.5 N.A. 96.9 92.7 N.A. 67.2 89.3 N.A. 83.6 N.A. 69 75.7 59.5 63.7
P-Site Identity: 100 N.A. N.A. 100 N.A. 100 100 N.A. 6.6 20 N.A. 6.6 N.A. 60 0 13.3 13.3
P-Site Similarity: 100 N.A. N.A. 100 N.A. 100 100 N.A. 13.3 33.3 N.A. 40 N.A. 86.6 20 26.6 20
Percent
Protein Identity: 27.3 N.A. N.A. N.A. N.A. 29
Protein Similarity: 46.6 N.A. N.A. N.A. N.A. 48.9
P-Site Identity: 13.3 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 33.3 N.A. N.A. N.A. N.A. 40
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 31 0 0 0 0 0 8 24 0 0 8 16 0 0 62 % A
% Cys: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 16 8 31 8 0 0 0 0 0 8 0 8 % D
% Glu: 0 0 0 39 0 16 16 0 8 8 0 0 47 0 8 % E
% Phe: 0 0 0 0 0 0 8 0 0 0 39 0 0 0 0 % F
% Gly: 31 0 16 8 8 0 0 16 8 0 0 0 16 0 0 % G
% His: 0 0 0 0 0 0 0 8 0 0 8 8 0 16 0 % H
% Ile: 0 0 0 0 0 0 8 0 0 0 0 8 0 0 0 % I
% Lys: 0 0 0 0 0 8 0 0 0 16 8 0 0 8 0 % K
% Leu: 16 39 8 0 24 0 39 0 77 16 16 47 8 16 8 % L
% Met: 0 0 39 0 0 0 0 0 0 0 0 0 0 8 8 % M
% Asn: 0 8 16 8 0 8 0 0 0 8 0 8 0 31 0 % N
% Pro: 0 8 0 0 0 0 0 0 8 0 8 8 0 0 0 % P
% Gln: 8 0 0 8 0 8 0 0 0 0 0 0 0 0 0 % Q
% Arg: 8 8 8 0 0 0 0 0 0 39 0 0 8 16 0 % R
% Ser: 0 0 8 0 24 8 8 47 0 0 0 8 0 0 0 % S
% Thr: 0 8 0 8 0 0 8 8 0 8 0 0 0 0 0 % T
% Val: 0 31 8 0 0 16 0 0 0 8 8 0 8 8 0 % V
% Trp: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 8 % W
% Tyr: 8 0 0 8 39 0 0 0 0 0 8 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _